Nickel-catalyzed C–H/N–H annulation of aromatic amides with alkynes in the absence of a specific chelation system† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc01750b Click here for additional data file.

Nickel-catalyzed C-H/N-H annulation of aromatic amides with alkynes in the absence of a specific chelation system.

The Ni-catalyzed reaction of aromatic amides with alkynes in the presence of KOBu t involves C-H/N-H oxidative annulation to give 1(2H)-isoquinolinones. A key to the success of the reaction is the use of a catalytic amount of strong base, such as KOBu t . The reaction shows a high functional group compatibility. The reaction with unsymmetrical alkynes, such as 1-arylalkynes, gives the correspon...

Rhodium(i)-catalyzed stereoselective [4+2] cycloaddition of oxetanols with alkynes through C(sp3)–C(sp3) bond cleavage† †Electronic supplementary information (ESI) available. CCDC 1512439 and 1512440. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc05246k Click here for additional data file. Click here for additional data file.

Rh(iii)-catalyzed double C–H activation of aldehyde hydrazones: a route for functionalized 1H-indazole synthesis† †Electronic supplementary information (ESI) available. CCDC 1499990. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc03888c Click here for additional data file. Click here for additional data file.

Rh-catalyzed aerobic oxidative cyclization of anilines, alkynes, and CO† †Electronic supplementary information (ESI) available: Experimental details and spectral data. See DOI: 10.1039/c7sc02181j Click here for additional data file.

Enantioselective synthesis of d-α-amino amides from aliphatic aldehydes† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc00064e Click here for additional data file. Click here for additional data file.